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Available Model Information


Model Name: Short name for the model. In case of modules the name is composed of the names for the two transcription factors involved.
Model: The table contains the parameters that were used to define the model using FastM.

For each individual element

  • the type of the element (e.g. Matrix or IUPAC),
  • the name of the element (e.g. matrix family used),
  • the DNA strand on which the element has to be found,
  • the parameters of the element (e.g. core and matrix similarity), and
  • the allowed distance range (in basepairs) to the following element
are listed.
Origin: This section shows information on the origin of the model, i.e.
  • a reference for further information on the model (e.g. experimental verification of the function of the model)
  • the gene description
  • the accession number of the sequence that was used for definition of the model
  • the organisms in which the module was defined and/or is evolutionarily conserved.
    If no organism is given, the module was defined in an organism that is not yet available in ElDorado. Please see the gene description in this case.
Sequence: The sequence of the promoter module is shown together with the accession number from which it has been extracted (±5 bp of the module match).
Function: A short description of the function of the model (e.g. how the model is involved in the regulation of the described promoter).
Quality Assessment: The quality assessment shows the results of quality checks applied to the models.

Examples are:

  • Number of false positive matches in a negative test set (false positive rate) with default ModelInspector threshold.
  • Number of matches per 10,000 basepairs in the human genome with default ModelInspector threshold.
Promoter Matches: The value given is the percentage of promoters in which a match to the module is found. The absolute number of promoter sequences with module match is given in parentheses. The following promoter sequences were scanned:
  • Vertebrate Modules: 314,000 human, mouse, and rat promoter sequences with an average length of 650 bp
  • Plant Modules: 71,000 promoter sequences of Arabidopsis thaliana and rice with an average length of 626 bp

Further information: